Content
ZOOHCC - 501: Molecular Biology (Theory)
Unit 1: Nucleic Acids
- Salient features and chemical compositions of DNA and RNA 2. Watson and Crick model of DNA; Structure and types of RNA click here
Unit 2: DNA Replication
- DNA Replication in prokaryotes click here
- DNA Replication in eukaryotic click here
- Mechanism of DNA replication click here
- Conservative, Semi-Conservative, Dispersive, The three models for DNA replication click here
- Bidirectional Replication click here
- Semi-discontinuous replication click here
- RNA priming, Okazaki fragment click here
- Replication of telomeres, Aging, function of telomeres click here
Unit 3: Transcription and Regulatory RNAs
- RNA polymerase and transcription Unit click here
- mechanism of transcription in prokaryotes click here
- mechanism of transcription in eukaryotes click here
- synthesis of rRNA and mRNA click here
- Transcription factors click here
- Ribo-switches, RNA interference, miRNA, siRNA click here
- Genetic code, Degeneracy of the genetic code and Wobble Hypothesis click here
- Process of protein synthesis in prokaryotes click here
- Ribosome structure and assembly in prokaryotes click here
- aminoacyl tRNA synthetases and charging of tRNA click here
- Proteins involved in initiation, elongation and termination of polypeptide chain click here
- Inhibitors of protein synthesis Difference between prokaryotic and eukaryotic translation click here
Unit 5: Post Transcriptional Modifications, Processing of Eukaryotic RNA and Gene Regulation
- Split genes: concept of introns and exons click here
- splicing mechanism, alternative splicing click here
- exon shuffling and RNA editing click here
- Processing of tRNA and rRNA click here
- Transcription regulation in prokaryotes click here
- Principles of transcriptional regulation with examples from lac operon and trp operon click here
